The classic methodology of inferring a phylogenetic tree from sequence data is composed of two steps. First, a multiple sequence alignment (MSA) is computed. Then, a tree is reconstructed assuming the ...

Traditionally, phylogeny and sequence alignment are estimated separately: first estimate a multiple sequence alignment and then infer a phylogeny based on the sequence alignment estimated in the ...

Scientists have found further evidence to support the idea that the primary two domains of life, the Archaea and Bacteria, are separated by a long phylogenetic tree branch and therefore distantly ...