In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...

When cancer cells are physically squeezed, they mount an instant, high-energy defense by rushing mitochondria to the cell nucleus, unleashing a surge of ATP that fuels DNA repair and survival. This ...

An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...

One hallmark of many biological processes is cellular phenotypic heterogeneity. Now, a new deep learning method—AINU (artificial intelligence [AI] of the nucleus)—can identify specific nuclear ...

(A) Experimental design. (B) Behavior assessments using open field tests. Heatmaps illustrate time spent (red) and movement trajectories (green). The PD group exhibited decreased movement speed ...