Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding ...

A study published in the Proceedings of the National Academy of Sciences has uncovered new clues to why some therapeutic proteins are so difficult to manufacture. The work—led by Nathan Lewis, PhD, ...

Researchers have successfully employed an algorithm to identify potential mutations which increase disease risk in the noncoding regions our DNA, which make up the vast majority of the human genome.

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

To ensure that protein production in our cells runs smoothly, the protein complex NAC slows down the rate of protein ...