Annotations of enzyme function provide critical starting points for generating and testing biological hypotheses, but the quality of functional annotations is hindered by uncertain assignments for ...

UPTON, NY - Scientists have long thought that individual enzymes have specific, single jobs dependent on their molecular shape. According to this premise, enzymes could only evolve to perform new ...

All life on Earth is unified by its use of a shared set of component chemical compounds and reactions, providing a detailed model for universal biochemistry. However, this notion of universality is ...

A research team at Leibniz-HKI has described a new enzyme that renders the highly toxic molecule malleicyprol harmless.

While E. coli is one of the most studied organisms, the function of 30% of proteins that make up E. coli has not yet been clearly revealed. For this, an artificial intelligence was used to discover ...

Using high-speed atomic force microscopy (HS-AFM), the Kanazawa University team led by Mikihiro Shibata filmed the dynamic movements of CaMKII at the single-molecule level. The images revealed that a ...

A multi-enzyme platform is developed for sequence-unconstrained traceless protein synthesis and modification with either synthetic peptides or recombinant proteins, according to a new study out of ...

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. The researchers said the AI tool, ...

Scientists have discovered a new function in a plant enzyme that could inspire the design of new chemical catalysts. The enzyme catalyzes, or initiates, one of the cornerstone chemical reactions ...

Patients with lupus are at increased risk of heart disease. Exposing endothelial cells -- known to protect against heart disease, in part by producing nitric oxide -- to the serum of patients with ...

Routine blood tests are increasingly detecting elevated liver enzymes, which may signal liver stress or damage. While mild increases can be harmless, persistently high or rapidly rising levels, ...