This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...
In the mutation accumulation experiment, amoebae were allowed to reproduce until they formed a visible plaque, and then one was picked at random and carried to a new plate where it was allowed to ...
James is a published author with multiple pop-history and science books to his name. He specializes in history, space, strange science, and anything out of the ordinary.View full profile James is a ...
Google DeepMind has wielded its revolutionary protein-structure-prediction AI in the hunt for genetic mutations that cause disease. A new tool based on the AlphaFold network can accurately predict ...
In the 1940s, the famous Luria–Delbrück experiment showed that bacteria evolve resistance to drugs they'd never encountered thanks to a random mutational process. When you purchase through links on ...
A microscopic flaw in the brain’s cellular scaffolding can shape brain size for life.
One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs ...
Scientists studying how microbes evolve have long assumed that nearly all new genetic mutations get passed down at a predictable pace and usually without either helping or hurting the microbe in ...
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