Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...
Ribosomes are fundamental molecular machines that translate mRNA sequences into polypeptides, ensuring the proper synthesis of proteins essential to cellular function. However, the fidelity of protein ...
News-Medical.Net on MSN
Two isoforms of a cellular energy sensor play distinct, opposing roles in Alzheimer's disease
A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest ...
News-Medical.Net on MSN
Nascent polypeptide-associated complex regulates early stages of protein formation
To ensure that protein production in our cells runs smoothly, the protein complex NAC slows down the rate of protein synthesis right at the start.
Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids, but cannot simply accumulate inside the cell forever. Once they have done their ...
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...
News Medical on MSN
How Cells Balance Their Protein Levels
EPFL researchers have discovered how cells help keep their protein levels steady even when their ability to make new proteins ...
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