Rational design, applying knowledge structure-function relationships into molecular design, has shown great promise in enzyme engineering, vaccine development, and inhibitor discovery. Using rational ...

An illustration of a self-assembling protein nanoparticle (SApNP) displaying Ebola virus surface proteins. This vaccine strategy is designed to help the immune system more effectively and respond to ...

Filoviruses get their name from the Latin word "filum," meaning thread-a reference to their long, filamentous shape. This virus family contains some of the most dangerous pathogens known to science, ...

Three scientists were named winners of the 2024 Nobel Prize in Chemistry for their innovations in the fields of computational protein design and structure prediction. One half of the prize was awarded ...

In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...