Researchers have solved the structure of a protein complex that helps determine the fate of human cells. Called a RISC-loading complex, this structure consists of small RNA molecules that control ...

BERKELEY, CA - The molecular architecture of a protein complex that helps determine the fate of human cells has been imaged for the first time by researchers with the U.S. Department of Energy's ...

Electron microscopy structure of the human RISC-loading complex, with the L-shaped Dicer enzyme shown as a wire map and the Argonaute2 protein, shown in purple. Disclaimer: AAAS and EurekAlert! are ...

MDRNA, Inc. (Nasdaq: MRNA) announced today positive in vivo efficacy data using a novel combination of a meroduplex siRNA and MDRNA’s proprietary lipid-based delivery platform, the DiLA 2 Platform.

miRNAs are conserved 21−22-nucleotide (nt) noncoding RNAs that downregulate gene expression post-transcriptionally (reviewed in ref. 1). In the nucleus, Drosha processes long primary miRNA (pri-miRNA) ...