The CEMIP enzyme inhibits the growth of oligodendrocytes and may serve as a therapeutic target to boost myelin repair in MS, ...

In this article, we examine ongoing challenges shaping target-based drug discovery and highlight how new technologies and ...

A team of researchers led by University of California, Riverside biomedical scientists has identified a small, previously overlooked small RNA molecule that plays a major role in controlling the ...

MPA-CF 3 specifically binds to COPZ1, a subunit of COPI. Upon binding, MPA-CF 3 destabilizes COPZ1 and disrupts the interaction of COPZ1 with the EV-A71 2C protein in a concentration-dependent manner.

Small molecule drugs dominate new drug approvals and are crucial for treating diverse diseases. They are typically low-weight, providing easy absorption and versatile delivery methods. Their simpler ...