Advancing RNA therapeutics depends on understanding two critical questions: Where do drug candidates go, and what do they do ...

STORM Therapeutics Ltd. (STORM), the clinical stage company pioneering cellular reprogramming through RNA modifications to treat disease, today announced a strategic collaboration ...

A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, according to a study led by Weill Cornell Medicine investigators. The ...

Researchers have developed a powerful tool capable of scanning thousands of biological samples to detect transfer ribonucleic acid (tRNA) modifications—tiny chemical changes to RNA molecules that help ...

Using a novel method, Weizmann Institute of Science researchers map 16 types of simultaneous changes in dozens of samples; ...

Once considered passive messengers of genetic information, RNA molecules are now understood to play an active and dynamic role in gene regulation, modulated by a rich layer of chemical modifications ...

New research published today in Nature from Ryan Flynn, MD, PhD, in collaboration with Vijay Rathinam, DVM, PhD, and his graduate student Vincent Graziano at UConn Health and other colleagues at ...

A new tool called SigRM helps researchers study RNA modifications in individual cells, improving our understanding of how genes are regulated. Researchers have developed a new tool that will help ...

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications. A ...

RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...