A context-driven memory model simulates a wide range of characteristics of waking and sleeping hippocampal replay, providing ...

Dynamic mechanisms of engram maturation. During the allocation, engram allocation is primarily governed by enhancements in intrinsic neuronal excitability, driven primarily by increased ...

In an important study for understanding how memories are made, cientists show that the flexibility of chromatin -- packaged DNA inside the cell -- plays a crucial role in 'deciding' which neurons are ...

Neuroscience continually strives to unravel the intricate relationship between neural network morphology, spiking dynamics, and their resulting functional ...

When a new memory forms the brain undergoes physical and functional changes known collectively as a “memory trace.” This memory trace represents the specific patterns of neuronal activity and ...

Neurons have variable levels of chromatin compaction, shown as different shades of red. The less compact a neuron, the more likely it is to be recruited into the memory trace (green). When we form a ...