Wnt Signaling Pathways: A Role In Pain Processing
Jun 11, 2025 · The Wnt/β-catenin signalling pathway, a conserved pathway essential for various fundamental activities, has been found to play a significant role in pathological bone formation …
Overview of the non-canonical Wnt signaling pathways (Wnt…
An elevation in Ca²⁺ level results in the activation of Ca²⁺-dependent signaling molecules, such as PKC, CAMKII and NFAT from publication: Wnt Signaling Pathways: A Role in Pain Processing ...
The Role of the Spinal Wnt Signaling Pathway in HIV-Related …
Feb 25, 2020 · This review summarizes the function of the spinal Wnt signaling pathway in HIV-induced neuropathic pain, focusing on the role of the spinal Wnt signaling pathway in HNP, …
Wnt signaling: A prospective therapeutic target for chronic pain
Mar 1, 2022 · Moreover, growing evidence shows that pharmacological blockage of aberrant activation of Wnt signaling pathways attenuates pain behaviors in animal models of chronic …
Post-translational modifications and secretion of Wnt proteins
Wnt ligands are the essential components of Wnt signaling pathways. Before binding to specific receptors, Wnt proteins experienced post-translational modification of acylation and N …
Wnt signaling: A prospective therapeutic target for chronic pain
Mar 1, 2022 · Moreover, growing evidence shows that pharmacological blockage of aberrant activation of Wnt signaling pathways attenuates pain behaviors in animal models of chronic …
Wnt Signaling in Pain | Encyclopedia MDPI
Oct 24, 2022 · Wnt signaling is activated at different levels along the pain pathway and in diverse cell types, depending on the chronic pain condition or the pain model studied (Figure 1). Most …
Wnt signaling pathways in biology and disease: mechanisms and ...
Apr 4, 2025 · The Wnt signaling pathway is critically involved in orchestrating cellular functions such as proliferation, migration, survival, and cell fate determination during development. …
The Role of the Spinal Wnt Signaling Pathway in HIV-Related …
Oct 1, 2020 · This review summarizes the function of the spinal Wnt signaling pathway in HIV-induced neuropathic pain, focusing on the role of the spinal Wnt signaling pathway in HNP, …
Wnt signaling pathway in spinal cord injury: from mechanisms to ...
Its pathophysiological processes are complex, with numerous molecules and signaling pathways intricately involved. Notably, the pronounced upregulation of the Wnt signaling pathway post …
National Center for Biotechnology Information
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The wingless-related integration site (Wnt) signaling pathway plays an essential role in embryonic development and nerv- ous system regulation. It is critically involved in multiple types of …
Regulation of Wnt Signaling Pathways at the Plasma Membrane …
Wnt signaling is one of the key signaling pathways that govern numerous physiological activities such as growth, differentiation and migration during development and homeostasis. As …
WNT Signaling in Disease | MDPI
Aug 3, 2019 · Abstract Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered …