DNA-encoded chemical library - Wikipedia
DNA-encoded chemical libraries (DECL) is a technology for the synthesis and screening on an unprecedented scale of collections of small molecule compounds. DECL is used in medicinal …
Challenges and Prospects of DNA-Encoded Library Data Interpretation
Nov 7, 2024 · DNA-encoded library (DEL) technology is a powerful platform for the efficient identification of novel chemical matter in the early drug discovery process enabled by parallel screening of vast …
Recent advances in DNA-encoded libraries - RSC Publishing
Jun 23, 2025 · The DNA-encoded library (DEL), a novel high-throughput screening platform that synergistically combines the strengths of combinatorial chemistry and genetic barcoding, has …
DNA-encoded chemical libraries - Nature Reviews Methods Primers
Jan 17, 2022 · DNA-encoded chemical library (DECL) technology is used by the pharmaceutical industry to discover small molecules capable of modulating biologically relevant targets.
DNA-encoded libraries (DELs): a review of on-DNA chemistries and …
A DNA-encoded library is a collection of small molecules covalently linked to DNA that has unique information about the identity and the structure of each library member.
What Is a DNA Encoded Chemical Library and How Does It Work?
Jul 31, 2025 · A DNA Encoded Chemical Library (DEL) is a scientific platform that merges chemistry and molecular biology to create vast collections of small molecules. This technology links each chemical …
DNA-Encoded Libraries | Springer Nature Link (formerly SpringerLink)
This book explores DNA-Encoded Library technology and discusses its use for hit validation and target identification.
Small-molecule discovery through DNA-encoded libraries - Nature
Jun 16, 2023 · Within the past 15 years, DNA-encoded library (DEL) technology has matured into a widely used platform for small-molecule discovery, yielding a wide variety of bioactive ligands for …
Future of Drug Discovery with DNA Encoded Libraries
One ground-breaking solution that has emerged in recent years is the utilization of DNA-encoded libraries (DELs). DELs stand as a versatile and potent technology foundation for uncovering small …
DNA-Encoded Chemical Libraries: A Comprehensive Review with …
Jun 14, 2021 · DNA-encoded chemical libraries (DELs) represent a versatile and powerful technology platform for the discovery of small-molecule ligands to protein targets of biological and …