Properdin is plasma glycoprotein that activates the complement system of the innate immune system. This protein binds to bacterial cell walls and dying human cells to stabilize the C3 and …

Properdin, the widely known positive regulator of the alternative pathway (AP), has undergone significant investigation over the last decade to define its function in inflammation and disease, …

Properdin, a positive regulator, is known to be essential in promoting complement activation on non-self surfaces. In the last decade, there has been increasing evidence to suggest that …

Citation: 'properdin' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. …

Key to the effects of the alternative pathway is properdin, a serum glycoprotein that can both initiate and positively regulate alternative pathway activity. Properdin is produced by many …

Sep 4, 2019 · Here, we report crystal structures of monomerized properdin, which was produced by co-expression of separate N- and C-terminal constructs that yielded monomer-sized …

Key to the effects of the alternative pathway is properdin, a serum glycoprotein that can both initiate and positively regulate alternative pathway activity. Properdin is produced by many …

Properdin (P), a regulatory protein of the alternative complement pathway (ACP) that stabilizes the ACP C3 convertase and thereby augments the density of C3b deposited following CP …

Properdin, the widely known positive regulator of the alternative pathway (AP), has undergone significant investigation over the last decade to define its function in inflammation and disease, …

The properdin gene is located on the X chromosome and deficiency leads to impaired alternative pathway function, leaving patients highly susceptible to fulminant meningococcal infections. …